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Major genes of general intelligence. (English)
Pers. Individ. Differ. 13, No. 10, 1115-1134 (1992).
Evidence in favour of the major gene theory of intelligence is stated in summary form. Empirical distributions from studies on giftedness by Terman and Weiss and data of social mobility can be explained by the existence of a major gene that in the homozygous state is the prerequisite to having an IQ of 130 or higher. Under the assumption of about 10\% misclassification of genotypes, family data are in agreement with Mendelian segregation at such a major gene locus. Elementary cognitive tasks, highly correlated with IQ, are not distributed normally. On the absolute scale of short-term memory capacity (measured in bits), defined as the product of memory span and mental speed, the heterozygotes are intermediate between the homozygotes. Where there are major genes, there must be an underlaying biochemical code, which can be detected. To this aim enzymes, responsible for the regulation of brain energy metabolism and correlated with IQ and social status, should be the target of further research. From the point of view of evolution, social stratification and the frequency of major genes of intelligence depend upon each other. (orig.)
Classification: C40
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