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Modeling Mendel\rq s laws on inheritance in computational biology and medical sciences. (English)
J. Educ. Technol. Syst. 39, No. 1, 31-46 (2010-2011).
Summary: The current research article is based on a simple and practical way of employing the computational power of widely available, versatile software MS Excel 2007 to perform interactive computer simulations for undergraduate/graduate students in biology, biochemistry, biophysics, microbiology, medicine in college and university classroom setting. To accomplish this important motive, we developed the necessary computer algorithm, which used a built-in pseudo-random number generating function in MS Excel 2007, to computer model two basic Mendel\rq s Laws of heredity for plant and animal species. We performed more than 18,000 computer simulations to investigate the behavior of dominant and recessive genes to verify two basic Mendel\rq s Laws of heredity. Our simulation work corroborates the experimental observations of Mendel\rq s research on inheritance in $Pisum hybrid species$. When we compare our results of simulated data with that of experiments done on $Drosophila melanogaster$, fruit fly extensively being used as a model organism to study genetics and development, an exceedingly good agreement between the simulated and the experimental data has been observed for the F2 generation.
Classification: R30 M60
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