Advanced Search

Query:

Fill in the form and click »Search«...

Format:

Display: entries per page entries

Zbl 1094.92025
Berger, John A.; Mitra, Sanjit K.; Carli, Marco; Neri, Alessandro
Visualization and analysis of DNA sequences using DNA walks. (English)
[J] J. Franklin Inst. 341, No. 1-2, 37-53 (2004). ISSN 0016-0032; ISSN 1879-2693/e

Summary: Visual methods illustrate how DNA sequences are read along a single DNA strand from the $5'$ end to the $3'$ end and they provide the hopes of gaining an understanding of the underlying genomic language. By handling genomic sequence residues as elements of a discrete-time signal, digital signal processing techniques can be employed for the analysis of genomic information. Using these representations and applying frequency domain transformations, it is shown that structures, or seemingly nonrandom behavior, may be readily identified in nucleotide sequences. We review the basic method of DNA walks and we show how these representations can be used to extract useful knowledge from the genomic data; namely long-range correlation information, sequence periodicities, and other sequence characteristics. Further information is elucidated through wavelet transform analysis. This work finally relates a measure of sequence complexity to these visual findings and offers conclusions regarding quantifying DNA sequence behavior or structure.

MSC 2000:: *92C40 Biochemistry, etc.
92C55 Tomography

Keywords: DNA sequence analysis; Complete genome sequences; Genome signal processing; DNA walk; Sequence complexity; Gauss-wavelet-based analysis

Comment on this Item PDF MathML XML ASCII DVI PS BibTeX Online Ordering Article Journal

	Scientific prize winners of the ICM 2010
	Overhang
	Lie groups, physics and geometry. An introduction for physicists, engineers and chemists.

Advanced Search

Zentralblatt MATH Berlin [Germany]