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A logistic model of periodic chemotherapy with drug resistance. (English) Zbl 0883.92016

Summary: A logistic model of periodic chemotherapy is developed that includes drug resistance. Criteria are developed to describe the acceptable number of doses before tumor regrowth due to drug resistance occurs. The model is then compared with some clinical results, and it is shown that they qualitatively match well.

MSC:

92C50 Medical applications (general)
34A05 Explicit solutions, first integrals of ordinary differential equations
39A10 Additive difference equations
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References:

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