\input zb-basic \input zb-ioport \iteman{io-port 05228748} \itemau{Sherali, Hanif D.; Van Goubergen, Dirk; Van Landeghem, Hendrik} \itemti{A quantitative approach for scheduling activities to reduce set-up in multiple machine lines.} \itemso{Eur. J. Oper. Res. 187, No. 3, 1224-1237 (2008).} \itemab Summary: The importance of ensuring short set-up times in manufacturing has been well-documented in the literature over the past years. However, this body of work largely addresses situations involving a single machine with no specific worker-related issues. In practice, there exist multiple machines or workstations that form a machine line, and that need set-up operations to be performed by multiple workers. The existing literature does not provide adequate methodologies for set-up reduction in such cases. This paper describes a quantitative modeling and algorithmic approach for scheduling activities or tasks in order to minimize the set-up time in such situations, also taking into account relevant secondary objectives such as balancing the workload amongst the workers, concentrating slack toward the end of the set-up process, and minimizing the movement costs of the workers performing the different set-up tasks. Three real-life examples are used to demonstrate the efficacy of the proposed approach. \itemrv{~} \itemcc{} \itemut{scheduling and sequencing; set-up times; set-up reduction; mixed-integer programming; cutting planes; network flows} \itemli{doi:10.1016/j.ejor.2006.06.068} \end