id: 05954267 dt: a an: 05954267 au: Higdon, David; Reese, C.Shane; Moulton, J.David; Vrugt, Jasper A.; Fox, Colin ti: Posterior exploration for computationally intensive forward models. so: Brooks, Steve (ed.) et al., Handbook of Markov chain Monte Carlo. Boca Raton, FL: CRC Press (ISBN 978-1-4200-7941-8/hbk; 978-1-4200-7942-5/ebook). Chapman \& Hall/CRC Handbooks of Modern Statistical Methods, 401-418 (2011). py: 2011 pu: Boca Raton, FL: CRC Press la: EN cc: ut: Metropolis algorithm; Markov chain Monte Carlo method ci: li: ab: From the introduction: In a common inverse problem, we wish to infer about an unknown spatial field $x=(x_1,\dots,x_m)^T$, given indirect observations $y=(y_i,\dots,y_n)^T$. The observations, or data, are linked to the unknown field $x$ through some physical system $y=ζ(x)+ε$, where $ζ(x)$ denotes the physical system and $ε$ is an $n$-vector of observation errors. Examples of such problems include medical imaging and cosmology. When a forward model, or simulator, of the physical process $η(x)$ is available, one can model the data using the simulator $y=η(x)+e$, where $e$ includes observation error as well as error due to the fact that the simulator $η(x)$ may be systematically different from reality $ζ(x)$ for input condition $x$. Our goal is to use the observed data $y$ to make inference about the spatial input parameters $x$ ‒ predict $x$ and characterize the uncertainty in the prediction for $x$. rv: