@article {IOPORT.05656547, author = {Besozzi, Daniela and Busi, Nadia and Cazzaniga, Paolo and Ferretti, Claudio and Leporati, Alberto and Mauri, Giancarlo and Pescini, Dario and Zandron, Claudio}, title = {(Tissue) P systems with cell polarity.}, year = {2009}, journal = {MSCS. Mathematical Structures in Computer Science}, volume = {19}, number = {6}, issn = {0960-1295}, pages = {1141-1160}, publisher = {Cambridge University Press, Cambridge}, doi = {10.1017/S0960129509990156}, abstract = {Summary: We consider the structure of the intestinal epithelial tissue and of cell-cell junctions as the biological model inspiring a new class of P systems. First we define the concept of cell polarity, a formal property derived from epithelial cells, which present morphologically and functionally distinct regions of the plasma membrane. Then we show two preliminary results for this new model of computation: on the theoretical side, we show that P systems with cell polarity are computationally (Turing) complete; on the modelling side, we show that the transepithelial movement of glucose from the intestinal lumen into the blood can be described by such a formal system. Finally, we define tissue P systems with cell polarity, where each cell has fixed connections to the neighbouring cells and to the environment, according to both the cell polarity and specific cell-cell junctions.}, identifier = {05656547}, }