\input zb-basic \input zb-ioport \iteman{io-port 05990728} \itemau{Antal, B\'alint; Hajdu, Andr\'as} \itemti{A stochastic approach to improve macula detection in retinal images.} \itemso{Acta Cybern. 20, No. 1, 5-15 (2011).} \itemab Summary: We present an approach to improve the detectors used in medical image processing by fine-tuning their parameters for a certain data set. The proposed algorithm uses a stochastic search algorithm to deal with large search spaces. We investigate the effectiveness of this approach by evaluating it on an actual clinical application. Namely, we present promising results with outperforming four state-of-the-art algorithms used for the detection of the center of the sharp vision (macula) in digital fundus images. \itemrv{~} \itemcc{} \itemut{biomedical image processing; simulated annealing; learning and adaptive systems} \itemli{} \end