\input zb-basic \input zb-ioport \iteman{io-port 06105335} \itemau{Xu, Hai-Qin; Ding, Yong-Sheng; Liu, Hao; Li, Xiao-Li} \itemti{An immune genetic algorithm with orthogonal initialization for analog circuit design.} \itemso{Huang, De-Shuang (ed.) et al., Intelligent computing theories and applications. 8th international conference, ICIC 2012, Huangshan, China, July 25--29, 2012. Proceedings. Berlin: Springer (ISBN 978-3-642-31575-6/pbk). Lecture Notes in Computer Science 7390. Lecture Notes in Artificial Intelligence, 59-66 (2012).} \itemab Summary: Evolutionary design of circuits (EDC) is an important branch of evolvable hardware (EHW). It is proved to be able to provide more optimized and diversified designs of circuit than human designs. An Orthogonal Immune Genetic Algorithm (OIGA) is proposed in this paper to improve the speed and efficiency of analog circuit design. Several factors, including the orthogonal initialization, the cloning selection operator, the hyper mutation operator, and the immune memory operator, are incorporated in the operation of OIGA. This algorithm makes use of the orthogonal design to select initialization population in order to preserve the diversity in the feasible solution space. The proposed algorithm is applied in the design of filter circuit. The simulation results show that OIGA can find the optimal solutions. The performance of the OIGA is compared with the Adaptive Immune Genetic Algorithm (AIGA) in optimizing a filter circuit. The results show that the OIGA is effective in improving the converging speed and the efficiency of the analog circuit design. \itemrv{~} \itemcc{} \itemut{Evolutionary design of circuits; Analog circuit; Orthogonal immune genetic algorithm; Cloning selection} \itemli{doi:10.1007/978-3-642-31576-3\_8} \end